Novel patient-centred approaches for survivorship, palliation and/or end-of-life care

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Domaine de recherche :
Type de financement :
Type d'instrument :
Recherche & Innovation Action
Deadline :
Mercredi 18 Avril 2018
Budget indicatif :
entre 3 et 4 millions d'euros par projet
Budget total :
44 millions d'euros
Code de l'appel : SC1-BHC-23-2018
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Specific Challenge:

Health conditions linked to end-of-life issues, acute and chronic pain, life-threatening non-communicable diseases, late or long term side effects and consequences of diseases and their treatments impact quality of life and pose an immense societal and economic burden. Palliative[1], end-of-life and survivorship care benefits patients with malignant and non-malignant chronic health conditions, providing relief from their symptoms and improving their quality of life. From 38% to 74.0% of the affected population[2] is estimated to be in need of palliative care. While a variety of interventions are in use, these are often not adequately validated or adapted to the specific needs of patients affected with a specific chronic disease or with multimorbidities. Therefore a need exists to strengthen the evidence base for available effective interventions improving quality of life in the domains of palliative, end-of-life and survivorship care.


Proposals should demonstrate, the effectiveness and cost-effectiveness of new, improved or specifically adapted pharmacological and/or non-pharmacological interventions to either relieve symptoms (e.g. pain) and suffering caused by life-threatening non-communicable diseases (including disabilities), or serious late and long-term side effects of disease treatments in patients and survivors, or symptoms that occur at the end of life. Randomised clinical trials or observational studies of new or improved patient and/or family centred[3] interventions, targeting children[4] and/or adults, should be considered for this topic. Proposals should give a sound feasibility assessment justified by available publications or preliminary results.

Proposals should prove the feasibility of integrating the proposed interventions in current pain management, palliative and/or end-of-life and/or survivorship care regimes and healthcare systems across Europe while taking into account the complex human aspects which are necessarily managed by such regimes and systems.

The proposals should address sex, gender, age and socio-economic factors in health and any other factors (e.g. ethical, familial, cultural considerations, including personal beliefs and religious perspectives, etc.) that could affect health equity.

Expected Impact:

  • Reduced symptom burden and suffering or improved well-being of patients in need of palliative, end-of-life or survivorship care and their formal and informal caregivers.
  • Improved clinical guidelines and policy recommendations with respect to pain management, palliative, end-of-life or survivorship care of patients with life-threatening non-communicable diseases or afflicted by late and long term side-effects of treatments.
  • Improved quality, effectiveness and cost-effectiveness of palliative, end-of-life or survivorship care services as well as access to care.
  • Reduced economic and wider societal burden arising from increased numbers of patients in need of palliative, end-of-life or survivorship care.